By Paul Wassarman

Advances in Developmental Biology used to be introduced as a sequence by way of JAI Press in 1992 with the looks of quantity 1. This sequence is inextricably associated with the better half sequence, Advances in Developmental Biochemistry , that used to be introduced while. As said within the Preface to quantity 1: ''Together the 2 sequence will supply annual studies of study issues in developmental biology/biochemistry, written from the views of prime investigators in those fields. it's meant that every overview draw seriously shape the author's personal learn contributions and point of view. hence, the displays are usually not inevitably encyclopedic in insurance, nor do they inevitably mirror all opposing perspectives of the subject.'' quantity 2 of the sequence follows those similar directions.

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Mol. Biol. Org. J. 10123-132. This Page Intentionally Left Blank MOLECULAR A N D GENETIC STUDIES OF H U M A N X CHROMOSOME INACTIVATION Carolyn J . Brown and Huntington F. Willard Preface . . . . . . . . . . . . . . . . . . . I. Introduction . . . . . . . . . . . . . . . . . . I1. Features of the Inactive X Chromosome . . . . . . . . . . 111. Activity of X-Linked Genes . . . . . . . . . . . . . A . Direct Analysis of Gene Expression . .

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1988). Location of the genes controlling H-Y antigen expression and testis determination on the mouse Y chromosome. Proc. Natl. Acad. Sci. USA 85:6442-6445. , and Taketo, T. (1991). Testicular differentiation in mammals under nonnal and experimental conditions. J. Electron Microsc. Techn. 19151171. , and Russell, E. S. (1957). Gene-induced embryological modifications of primordial germ cells in the mouse. J. Exp. 134:207-237. Mitchell, M. , Woods, D. R.. Tucker, P. ,Opp, J. , and Bishop, C. E.

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